用英语关心他人，以下表达很实用：

1. 啥事让你如何不高兴？What's got you so down?

2. 你没事吧。Are you feeling alright?

3. 你想跟我聊一聊吗？Would you like to talk about it?

4. 你随时可以跟我聊。If you want someone to talk to, I'm always there.